bpAmaral JD, Herrera F, Rodrigues PM, Dionísio PA, Outeiro TF, Rodrigues CM.
Live-cell imaging of p53 interactions using a novel Venus-based bimolecular fluorescence complementation system.
Biochem Pharmacol. 2012 Dec 19. doi:pii: S0006-2952(12)00795-2. 10.1016/j.bcp.2012.12.009. PubMed





Guerreiro PS, Huang Y, Gysbers A, Cheng D, Gai WP, Outeiro TF, Halliday GM.
LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell models.
J Mol Med (Berl). 2012 Nov 27. PubMed




jbmRepici M, Straatman KR, Balduccio N, Enguita FJ, Outeiro TF, Giorgini F.
Parkinson’s disease-associated mutations in DJ-1 modulate its dimerization in living cells.
J Mol Med (Berl). 2012 Nov 27. PubMed




sbMarques S, Outeiro TF.
Epigenetics in Parkinson’s and Alzheimer’s diseases.
Subcell Biochem. 2012;61:507-25. doi: 10.1007/978-94-007-4525-4_22. PubMed




brbLopes da Fonseca T, Correia A, Hasselaar W, van der Linde HC, Willemsen R, Outeiro TF.
The zebrafish homologue of Parkinson’s disease ATP13A2 is essential for embryonic survival.
Brain Res Bull. 2012 Oct 31;90C:118-126. doi: 10.1016/j.brainresbull.2012.09.017. PubMed




jnsDiógenes MJ, Dias RB, Rombo DM, Miranda HV, Maiolino F, Guerreiro P, Näsström T, Franquelim HG, Oliveira LM, Castanho MA, Lannfelt L, Bergström J, Ingelsson M, Quintas A, Sebastião AM, Lopes LV, Outeiro TF.
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.
J Neurosci. 2012 Aug 22;32(34):11750-62. PubMed




nsMarques SC, Lemos R, Ferreiro E, Martins M, de Mendonça A, Santana I, Outeiro TF, Pereira CM.
Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice.
Neuroscience. 2012 Sep 18;220:256-66. Epub 2012 Jun 21. PubMed




jbcPetroi D, Popova B, Taheri-Talesh N, Irniger S, Shahpasandzadeh H, Zweckstetter M, Outeiro TF, Braus GH.
Aggregate Clearance of α-Synuclein in Saccharomyces cerevisiae Depends More on Autophagosome and Vacuole Function Than on the Proteasome.
J Biol Chem. 2012 Aug 10;287(33):27567-79. Epub 2012 Jun 21. PubMed




cddMarques O, Outeiro TF.
Alpha-synuclein: from secretion to dysfunction and death.
Cell Death Dis. 2012 Jul 19;3:e350. doi: 10.1038/cddis.2012.94. PubMed




noaKemppainen S, Rantamäki T, Jerónimo-Santos A, Lavasseur G, Autio H, Karpova N, Kärkkäinen E, Stavén S, Miranda HV, Outeiro TF, Di ógenes MJ, Laroche S, Davis S, Sebastião AM, Castrén E, Tanila H.
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.
Neurobiol Aging. 2012 Jun;33(6):1122.e23-39. Epub 2011 Dec 30. PubMed




embommMaxwell MM, Zaldivar-Jolissaint JF, Mai A, Outeiro TF, Kazanstev AG.
Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease.
EMBO Mol Med. 2012 May 18. doi: 10.1002/emmm.201201452. PubMed




noaSzegö EM, Outeiro TF, Kermer P, Schulz JB.
Impairment of the septalcholinergic neurons in MPTP-treated A30P α-synuclein mice.
Neurobiol Aging. 2012 May 11. PubMed




fpde Oliveira RM, Sarkander J, Kazantsev AG, Outeiro TF.
SIRT2 as a Therapeutic Target for Age-Related Disorders.
Front Pharmacol. 2012; 3:82. Epub 2012 May 3. PubMed




fpKazantsev AG, Outeiro TF.
Editorial on special topic: sirtuins in metabolism, aging, and disease.
Front Pharmacol. 2012;3:71. Epub 2012 Apr 24. PubMed




cRosa P, Tenreiro S, Chu V, Outeiro TF, Conde JP.
High-throughput study of alpha-synuclein expression in yeast using microfluidics for control of local cellular microenvironment.
Biomicrofluidics. 2012 Mar 6 (1):14109-141099. Epub 2012 Feb 9. PubMed




hmgSancenon V, Lee SA, Patrick C, Griffith J, Paulino A, Outeiro TF, Reggiori F, Masliah E, Muchowski PJ.
Suppression of α-Synuclein Toxicity and Vesicle Trafficking Defects by Phosphorylation at S129 in Yeast Depends on Genetic Context.
Hum Mol Genet. 2012 Feb 21. PubMed




meHerrera F, Gonçalves S, Outeiro TF.
Imaging protein oligomerization in neurodegeneration using bimolecular fluorescence complementation.
Methods Enzymol. 2012;506:157-74. PubMed PMID: 22341224.