2013

1Wales P, Pinho R, Lázaro DF, Outeiro TF.
Limelight on alpha-synuclein: pathological and mechanistic implications in neurodegeneration.
J Parkinsons Dis. 2013 PubMed

 

 

 

1Basso E, Antas P, Marijanovic Z, Gonçalves S, Tenreiro S, Outeiro TF.
PLK2 Modulates α-Synuclein Aggregation in Yeast and Mammalian Cells.
Mol Neurobiol. 2013 May 17. PubMed

 

 

 

jmmAmaral M, Outeiro TF, Scrutton NS, Giorgini F.
The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease.
J Mol Med (Berl). 2013 May 1. PubMed

 

 

 

jmmEisbach SE, Outeiro TF.
alpha-Synuclein and intracellular trafficking: impact on the spreading of Parkinson’s disease pathology.
J Mol Med (Berl). 2013 Apr 25. PubMed

 

 

 

gsFaria C, Jorge CD, Borges N, Tenreiro S, Outeiro TF, Santos H.
Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson’s disease.
Biochim Biophys Acta. 2013 Apr 19. doi:pii: S0304-4165(13)00143-8. 10.1016/j.bbagen.2013.04.015. PubMed

 

 

 

jonTenreiro S, Munder MC, Alberti S, Outeiro TF.
Harnessing the power of yeast to unravel the molecular basis of neurodegeneration.
J Neurochem. 2013 Apr 20. doi: 10.1111/jnc.12271. PubMed

 

 

 

natureAmaral M, Levy C, Heyes DJ, Lafite P, Outeiro TF, Giorgini F, Leys D, Scrutton NS.
Structural basis of kynurenine 3-monooxygenase inhibition.
Nature. 2013 Apr 18;496(7445):382-5. doi: 10.1038/nature12039. Epub 2013 Apr 10. PubMed

 

 

 

gsFaria C, Jorge CD, Borges N, Tenreiro S, Outeiro TF, Santos H.
Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson´s disease.
Biochim Biophys Acta. 2013 Apr 19. doi:pii: S0304-4165(13)00143-8. 10.1016/j.bbagen.2013.04.015. PubMed

 

 

 

anaTaschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P, Benz R, Becker S, Outeiro TF, Looger L, Bähr M, Zweckstetter M, Kügler S..
ß-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
Ann Neurol. 2013 Mar 28. doi: 10.1002/ana.23905. PubMed

 

 

 

jonMiranda HV, Xiang W, de Oliveira RM, Simões T, Pimentel J, Klucken J, Penque D, Outeiro TF.
Heat-mediated enrichment of α-synuclein from cells and tissue for assessing post-translational modifications.
J Neurochem. 2013 Mar 27. doi: 10.1111/jnc.12251. PubMed

 

 

 

jonSchildknecht S, Gerding HR, Karreman C, Drescher M, Lashuel HA, Outeiro TF, Di Monte DA, Leist M.
Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies.
J Neurochem. 2013 Mar 1. doi: 10.1111/jnc.12226. PubMed

 

 

 

embommDonmez G, Outeiro TF.
SIRT1 and SIRT2: emerging targets in neurodegeneration.
EMBO Mol Med. 2013 Feb 18. doi: 10.1002/emmm.201302451. PubMed

 

 

 

1Gonçalves S, Outeiro TF.
Assessing the Subcellular Dynamics of Alpha-synuclein Using Photoactivation Microscopy.
Mol Neurobiol. 2013 Feb 8. PubMed