2017

1 Elodie Marciniak, Antoine Leboucher, Emilie Caron, Tariq Ahmed, Anne Tailleux, Julie Dumont, Tarik Issad, Ellen Gerhardt, Patrick Pagesy, Margaux Vileno, Clément Bournonville, Malika Hamdane, Kadiombo Bantubungi, Steve Lancel, Dominique Demeyer, Sabiha Eddarkaoui, Emmanuelle Vallez, Didier Vieau, Sandrine Humez, Emilie Faivre, Benjamin Grenier-Boley, Tiago F. Outeiro, Bart Staels, Philippe Amouyel, Detlef Balschun, Luc Buee, David Blum.
Tau deletion promotes brain insulin resistance.
JEM. 2017 Jun 26, PubMed

 

 

 

1 Paiva I, Pinho R, Pavlou MA, Hennion M, Wales P, Schütz AL, Rajput A, Szego ÉM, Kerimoglu C, Gerhardt E, Rego AC, Fischer A, Bonn S, Outeiro TF.
Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage..
Hum Mol Genet. 2017 Jun 15, PubMed

 

 

 

1 Turriani E, Lázaro DF, Ryazanov S, Leonov A, Giese A, Schön M, Schön MP, Griesinger C, Outeiro TF, Arndt-Jovin DJ, Becker D.
Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death..
Proc Natl Acad Sci. 2017 Jun 5, PubMed

 

 

 

1 Moreira S, Fonseca I, Nunes MJ, Rosa A, Lemos L, Rodrigues E, Carvalho AN, Outeiro TF, Rodrigues CMP, Gama MJ, Castro-Caldas M.
Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson’s disease..
Exp Neurol. 2017 May 25,PubMed

 

 

 

1 Pavlou MAS, Outeiro TF.
Epigenetics in Parkinson’s Disease..
Adv Exp med Biol. 2017 May 19,PubMed

 

 

 

1 Lázaro DF, Pavlou MAS, Outeiro TF.
Cellular models as tools for the study of the role of alpha-synuclein in Parkinson’s disease..
Exp Neurol. 2017 May 16,PubMed

 

 

 

1 Szegő ÉM, Gerhardt E, Outeiro TF.
Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway..
Neurobiol Aging. 2017 April 10, PubMed

 

 

 

1 Vicente Miranda H, Szego ÉM, Oliveira LM, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF.
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies..
Brain. 2017 April 10, PubMed

 

 

 

1 de Oliveira RM, Vicente Miranda H, Francelle L, Pinho R, Szegö ÉM, Martinho R, Munari F, Lázaro DF, Moniot S, Guerreiro P, Fonseca L, Marijanovic Z, Antas P, Gerhardt E, Enguita FJ, Fauvet B, Penque D, Pais TF, Tong Q, Becker S, Kügler S, Lashuel HA, Steegborn C, Zweckstetter M, Outeiro TF.
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease..
PLoS Biol. 2017 Mar 3
.PubMed

 

 

 

1 Menges S, Minakaki G, Schaefer PM, Meixner H, Prots I, Schlötzer-Schrehardt U, Friedland K, Winner B, Outeiro TF, Winklhofer KF, von Arnim CA, Xiang W, Winkler J, Klucken J.
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress..
SciRep. 2017 Feb 22 PubMed

 

 

 
1 Cukierman DS, Pinheiro AB, Castiñeiras-Filho SL, da Silva AS, Miotto MC, De Falco A, de P Ribeiro T, Maisonette S, da Cunha AL, Hauser-Davis RA, Landeira-Fernandez J, Aucélio RQ, Outeiro TF, Pereira MD, Fernández CO, Rey NA.
A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson’s disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies..
J Inorg Biochem. 2017 Feb 22
.PubMed

 

 

 
1 Tenreiro S, Franssens V, Winderickx J, Outeiro TF.
Yeast models of Parkinson’s disease-associated molecular pathologies..
Curr Opin Genet Dev. 2017 Feb 16
. PubMed

 

 

 
1 Villar-Piqué, Rossetti, Ventura, Carloni, Fernández, Outeiro TF.
Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics..
Communicative & Integrative Biology. 2017 Feb 6
.PubMed

 

 

 
1 Francelle L, Lotz C, Outeiro T, Brouillet E, Merienne K.
Contribution of Neuroepigenetics to Huntington’s Disease. Front Hum Neurosci.
2017 Jan 30
.PubMed

 

 

 

1 Pardo J, Abba MC, Lacunza E, Francelle L, Morel GR, Outeiro TF, Goya RG.
Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats.

January 17, 2017.
.PubMed