Publikationen

Originalarbeiten

2011

Kemppainen S, Rantamäki T, Jerónimo-Santos A, Lavasseur G, Autio H, Karpova N, Kärkkäinen E, Stavén S, Miranda HV, Outeiro TF, Diógenes MJ, Laroche S, Davis S, Sebastião AM, Castrén E, Tanila H.
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.
Neurobiol Aging. 2011 Dec 29. [Epub ahead of print]
PubMed PMID: 22209410.

Gerhardt E, Gräber S, Szegö EM, Moisoi N, Martins LM, Outeiro TF, Kermer P.
Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice.
PLoS One. 2011;6(12):e28855. Epub 2011 Dec 19.
PubMed PMID: 22205977.

Herrera F, Outeiro TF
α-Synuclein modifies huntingtin aggregation in living cells.
FEBS Lett. 2011 Nov 24. [Epub ahead of print]
PubMed PMID: 22119730.

Näsström T, Gonçalves S, Sahlin C, Nordström E, Screpanti Sundquist V, Lannfelt L, Bergström J, Outeiro TF, Ingelsson M
Antibodies against Alpha-Synuclein Reduce Oligomerization in Living Cells.
PLoS One 2011;6(10):e27230. Epub 2011 Oct 31.
PubMed PMID: 22073131; PubMed Central PMCID: PMC3205056.

Ribeiro Morais G, Vicente Miranda H, Santos IC, Santos I, Outeiro TF, Paulo A.
Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes
Bioorg Med Chem. 2011 Oct 18. [Epub ahead of print].
PMID: 22078413.

Badiola N, de Oliveira RM, Herrera F, Guardia-Laguarta C, Gonçalves SA, Pera M, Suárez-Calvet M, Clarimon J, Outeiro TF, Lleó A.
Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy.
PLoS One. 2011;6(10):e26609. Epub 2011 Oct 24.
PMID: 22039514

Martins M, Rosa A, Guedes LC, Fonseca BV, Gotovac K, Violante S, Mestre T, Coelho M, Rosa MM, Martin ER, Vance JM, Outeiro TF, Wang L, Borovecki F, Ferreira JJ, Oliveira SA.
Convergence of miRNA Expression Profiling, α-Synuclein Interacton and GWAS in Parkinson's Disease.
PLoS One. 2011;6(10):e25443. Epub 2011 Oct 7.
PubMed PMID: 22003392.

Swinnen E, Büttner S, Outeiro TF, Galas MC, Madeo F, Winderickx J, Franssens
V. Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast.
Biochem Soc Trans. 2011 Oct 1;39(5):1476-81.
PubMed PMID: 21936837.

Outeiro TF.
Amyloidogenesis: FlAsH illuminates Aß aggregation.
Nat Chem Biol. 2011 Aug 17;7(9):581-2. doi: 10.1038/nchembio.636. No abstract available.
PMID: 21849997.

Szego EM, Gerhardt E, Outeiro TF, Kermer P
Dopamine-depletion and increased alpha-synuclein load induce degeneration of cortical cholinergic fibers in mice.
J Neurol Sci. 2011 Jul 18. [Epub ahead of print]
PubMed PMID: 21774947.

de Oliveira RM, Marijanovic Z, Carvalho F, Miltenyi GM, Matos JE, Tenreiro S, Oliveira S, Enguita FJ, Outeiro TF.
Impaired proteostasis contributes to renal tubular dysgenesis.
PLoS One. 2011;6(6):e20854. Epub 2011 Jun 9.
Epub 2011 Jun 9.PubMed PMID: 21695262; PubMed Central PMCID: PMC3111453.
Marques S, Batalha VL, Lopes LV, Outeiro TF.
Modulating Alzheimer's Disease Through Caffeine: A Putative Link to Epigenetics.
J Alzheimers Dis. 2011 Mar 21.
PubMed PMID: 21427489.
Jorge CD, Ventura R, Maycock C, Outeiro TF, Santos H, Costa J.
Assessment of the Efficacy of Solutes from Extremophiles on Protein Aggregation in Cell Models of Huntington's and Parkinson's Diseases.
Neurochem Res. 2011 Mar 17.
PubMed PMID: 21416120.
Hansen C, Angot E, Bergström AL, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li JY, Brundin P.
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.
J Clin Invest. 2011 Feb 1;121(2):715-25. doi: 10.1172/JCI43366. Epub 2011 Jan 18.
PubMed PMID: 21245577; PubMed Central PMCID: PMC3026723.
Herrera F, Tenreiro S, Miller-Fleming L, Outeiro TF.
Visualization of cell-to-cell transmission of mutant huntingtin oligomers.
PLoS Curr. 2011 Feb 11;3:RRN1210.
PubMed PMID: 21331289; PubMed Central PMCID: PMC3037516.