Protein quality control mechanisms, required for normal cellular functioning, encompass multiple functions related to protein production and maintenance. However, […]
Self-splicing introns are mobile elements that have invaded a number of highly conserved genes in prokaryotic and organellar genomes. […]
As the physical barrier between the cell and the outside environment, the plasma membrane is well-positioned to be the […]
On January 26 at the Neurosciences Research Building (BIN/DZNE) we celebrated the 4th Night of Science in Göttingen. For […]
Life expectancy has increased and current world leading causes of death are agerelated diseases. Diverse of such […]
Aggregation of alpha-synuclein (ASYN) in Lewy bodies and Lewy neurites is the typical pathological hallmark of Parkinson’s […]
Sirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously […]
Synucleinopathies are a group of progressive disorders characterized by the abnormal aggregation and accumulation of α-synuclein (aSyn), an abundant […]
α-Synuclein misfolding and aggregation is a hallmark in Parkinson’s disease and in several other neurodegenerative diseases known as synucleinopathies. […]
Synucleinopathies, such as Parkinson’s disease and dementia with Lewy bodies, are neurodegenerative disorders that are characterized by the accumulation […]